Treatment strategies for pediatric idiopathic hypercalciuria.
نویسندگان
چکیده
Idiopathic hypercalciuria (IH) is a common metabolic disorder in children and is associated with the development of renal calculi, nephrocalcinosis, hematuria and osteopenia. The effect of various dietary modifications and available pharmacologic therapies on reducing urinary calcium excretion and/or urinary supersaturation is discussed in this article. The importance of a multidisciplinary approach involving the patient, their families, and health-care professionals is also addressed.
منابع مشابه
Role of high-dose hydrochlorothiazide in idiopathic hypercalciuric urolithiasis of childhood.
INTRODUCTION The aim of this study was to evaluate the role of hydrochlorothiazide in pediatric calculus formers with hypercalciuria and define possible factors affecting response to treatment. MATERIALS AND METHODS Nineteen pediatric calculus formers, 12 girls and 7 boys, aged 15 days to 60 months, with idiopathic hypercalciuria received high-dose hydrochlorothiazide (1 mg/kg/d to 2 mg/kg/d)...
متن کاملClinical manifestations of pediatric idiopathic hypercalciuria.
Idiopathic hypercalciuria (IH) is a common metabolic disorder in children with protean manifestations, many of which can mimic other common pediatric diseases. Reports in the medical literature describe children with IH presenting with a wide array of calculi and non-calculi related clinical symptoms such as hematuria, urinary tract infections (UTIs), urgency, urinary incontinence and recurrent...
متن کاملMolecular mechanisms of primary hypercalciuria.
Nephrolithiasis, with a lifetime incidence of up to 13% (1–9), results in significant morbidity as well as substantial economic costs, not only directly from medical treatment but also indirectly through time lost from work. Approximately 70% of kidney stones are composed of calcium, generally combined with oxalate and/or phosphate (1,7). Hypercalciuria is the most consistent metabolic abnormal...
متن کاملTreatment of idiopathic hypercalciuria and its impact on associated diseases.
UNLABELLED Idiopathic hypercalciuria may be associated with urinary tract infection, hematuria, nephrolithiasis and osteopenia. In order to describe the occurrence of these concurrent conditions related to the variation in urinary calcium and hypercalciuria response to sequential therapy, with a normal protein and low sodium diet, potassium citrate and hydrochlorothiazide; 46 patients older tha...
متن کاملCalculus disease of the urinary tract at a district hospital.
At a District General Hospital the organization of a clinic for the investigation and treatment of patients with calculus disease of the urinary tract is described. The way in which such a clinic may be orgainzed is discussed and the results presented. In patients with idiopathic hypercalciuria, sodium cellulose phosphate causes a significant reduction in urinary calcium levels when used in suc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Frontiers in bioscience
دوره 1 شماره
صفحات -
تاریخ انتشار 2009